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  • The discovery of acetyl-CoA in 1947 by Fritz Albert Lipmann was another major contribution.
  • It was proposed to be the intermediary molecule between energy-yielding and energy-requiring reactions in cells by Fritz Albert Lipmann in 1941.
  • During this period, Lundsgaard was preoccupied as physiology department chair, consequently Fritz Albert Lipmann, who had recently fled Germany, served as Kalckar's research mentor.
  • In this " squiggle " notation, ATP becomes A-P ~ P ~ P . The squiggle notation was invented by Fritz Albert Lipmann, who first proposed ATP as the main energy transfer molecule of the cell, in 1941.
  • This discovery was followed in the early 1940s by the work of Herman Kalckar, who established the link between the oxidation of sugars and the generation of ATP . This confirmed the central role of ATP in energy transfer that had been proposed by Fritz Albert Lipmann in 1941.
  • In 1939, experiments using minced muscle cells demonstrated that cellular respiration using one oxygen atom can form two adenosine triphosphate ( ATP ) molecules, and, in 1941, the concept of the phosphate bonds of ATP being a form of energy in cellular metabolism was developed by Fritz Albert Lipmann.